BacPREP was established to enable epidemic preparedness and response for bacterial infections, by conducting research and supporting the WHO Collaborative Open Research Consortium (CORC) on priority bacterial pathogens.
The WHO Collaborative Open Research Consortium (CORC) for priority bacterial pathogens is a globally representative, collaborative group supported our team at LSHTM and partners at the Aga Khan University, Pakistan. Our primary objective is to accelerate the development of medical countermeasures directed against bacterial pathogens prioritised by WHO Health Emergencies (Vibrio cholerae, Yersinia pestis, Shigella spp., non-typhoidal Salmonella serovars Enteritidis and Typhimurium, and Klebsiella pneumoniae.)
BacPREP includes experts in vaccines, diagnostics, therapeutics, data science, social science, public health, and policy.
BacPREP at LSHTM was established to enable epidemic preparedness and response for bacterial infections. We work closely with the BacPREP at Aga Khan University, led by Prof. Farah Qamar, to supporting the WHO Collaborative Open Research Consortium (CORC) on priority bacterial pathogens.
Leadership
- Co-Director, Dr. Megan E. Carey, LSHTM
- Co-Director, Prof. Kathryn Holt, LSHTM Centre for Antimicrobial Resistance
Advisory group
BacPREP activities are informed by a strategic advisory group comprising LSHTM researchers across a variety of domains:
- Prof. Adam Kucharski, Centre for Epidemic Preparedness and Response, NIHR Health Protection Research Unit in Health Analytics and Modelling
- Prof. Gwenan Knight, Centre for Mathematical Modelling of Infectious Diseases
- Prof. Brendan Wren, Vaccine Centre
- Prof. Clare Chandler, Centre for Evaluation
- Assistant Prof. Nadine Beckman, LSHTM and UK Public Health Research Team (UK-PHRST)
- Prof. Nicholas Thomson, LSHTM and
- Dr. Charlene Rodrigues, LSHTM and UKHSA, NIHR HPRU in Public Health Genomics
Following the release of the at the in Rio de Janeiro, the is moving forward with the new framework for research preparedness and response. This framework promotes a broad-based research approach across all pathogen families, irrespective of their future epidemic or pandemic potential.
A key action within this strategy is the establishment of independent Collaborative Open Research Consortium (CORC) for each pathogen family. Moving to implementation of this new strategy, the WHO R&D Blueprint are partnering with different research institutions to set up these CORCs. Each will be anchored by a .
Each CORC will serve as a coordinating mechanism to establish unified global R&D agendas for various pathogen families. Functioning as a peer-reviewed process, it aims to prioritise research areas critical for the development of medical countermeasures. Its primary role is to advance scientific knowledge and guide research efforts, fostering equitable contributions, particularly from the Global South, to ensure inclusive and balanced global collaboration.
The Bacterial Pathogen Research and Emergency Preparedness (BacPREP) CORC was established to bring together a globally representative, multidisciplinary group of researchers to identify key research gaps and conduct supportive activities to accelerate the development and deployment of medical countermeasures directed against priority bacterial pathogens, Vibrio cholerae, Yersinia pestis, Shigella spp., non-typhoidal Salmonella serovars Enteritidis and Typhimurium, and Klebsiella pneumoniae.
The BacPREP CORC is co-led by LSHTM and Aga Khan University. Read our CORC page to see our working group leads. The CORC is open to all, see the Contact box on the left for how to get involved.
In collaboration with the Aga Khan University (AKU) in Pakistan, we have established a Collaborative Open Research Consortium (CORC) on Bacterial Pathogen Research and Emergency Preparedness (BacPREP) to convene a multidisciplinary and globally representative group of researchers to identify research and development priorities to accelerate the development of medical countermeasures directed against priority bacterial pathogens.
CORC Co-leads
- Dr. Megan E. Carey, °®ÍþÄÌapp of Hygiene & Tropical Medicine, UK
- , Aga Khan University, Pakistan
Pathogen Working Group Leads
Invasive non-typhoidal Salmonella (serovars Enteritidis and Typhimurium)
- , Imperial College, UK
- , Institute for Molecular Bioscience, University of Queensland, Australia
Klebsiella pneumoniae
- , St. Andrews, UK
- Prof. Kat Holt, °®ÍþÄÌapp of Hygiene & Tropical Medicine, UK
- , Child Health Research Foundation, Bangladesh
Shigella spp.
- , Doherty Institute, University of Melbourne, Australia
- , Institut Pasteur, France
Vibrio cholerae
- , icddr,b, Bangladesh
- , Wellcome Sanger Institute, UK
Yersinia pestis
- , Institut Pasteur, France
The first objective of the CORC is to develop a research and development roadmap that outlines key priorities and strategic goals in the development of medical countermeasures against priority bacterial pathogens.
