Dr Katharina Kranzer
Clinical Associate Professor in Infectious Disease Epidemiology
United Kingdom
Based in Harare, Zimbabwe, I serve as Director of the Health Research Unit Zimbabwe (), part of the Biomedical Research and Training Institute (BRTI). I hold academic appointments at the °®ÍþÄÌapp of Hygiene & Tropical Medicine and Ludwig Maximilian University of Munich.
My research focuses on tuberculosis (TB), antimicrobial resistance, and health systems in high-burden settings. My PhD (Wellcome Trust-funded, 2008–2011) examined active TB case finding and ART for TB control in high HIV prevalence contexts. From 2015 to 2018, I directed Germany’s National and WHO Supranational TB Reference Laboratory at the Research Centre Borstel.
I co-lead the EDCTP-funded study with Dr. Norbert Heinrich, aiming to evaluate novel diagnostic tools for early TB detection and targeted preventive treatment. I also serve as Chief Scientist on the TB-CAPT cluster-randomised trial, assessing the impact of near-patient diagnostics (Omni Xpert/Ultra) on treatment initiation timelines.
My work in antimicrobial resistance includes studies in Harare with Dr. Tom Darton (University of Sheffield) and Dr. Justin Dixon, evaluating the impact of the 2019 typhoid conjugate vaccine campaign on antibiotic prescribing.
I contribute to global policy as a member of WHO guideline development groups on TB screening, diagnostics, and testing tools.
I am deeply committed to research capacity development. I co-direct the Africa Health Research Training Programme () African matched fellowship scheme, and lead the Southern African Research Capacity Network (), supporting emerging researchers across the region.
Affiliations
°®ÍþÄÌapp
Teaching
I have a longstanding and active commitment to teaching, training, and research capacity strengthening. I previously served as module organiser and lecturer for the HIV module at LSHTM in London and have contributed as a tutor to the distance learning MSc in Epidemiology for over a decade. I also supervise MSc student projects and (co)supervise several PhD and DrPH students, the majority of whom are based in Zimbabwe and engaged in field-based research.
I am a faculty member on the NIH Fogarty Training for Research Excellence and Mentorship in Tuberculosis (TRENT) programme in Zimbabwe. I serve as co-director of the CREATE PhD programme in Zimbabwe and co-lead, together with Professor Helen Ayles, the CREATE stream supporting matched African fellows. Additionally, I coordinate the EDCTP-funded SOFAR Fellowship Programme, which supports the training of four MSc students, six PhD fellows, and five postdoctoral researchers across Zimbabwe, Zambia, and Mozambique.
My work is underpinned by a strong commitment to capacity building in public health and laboratory systems. During my tenure as Director of the WHO Supranational Tuberculosis Reference Laboratory, I established collaborative partnerships with national and regional laboratories in Moldova, Azerbaijan, Armenia, Sierra Leone, Pakistan, and Ghana. This included delivering in-country training on molecular diagnostics, laboratory information systems, and quality management, alongside supervisory and technical support visits.
In Zimbabwe, I have led the development of a diagnostic blood and urine culture service at the Biomedical Research and Training Institute (BRTI). I am actively involved in laboratory-based training, including bench supervision, regular bench rounds, and structured feedback on standard operating procedures developed by junior staff. I view laboratory quality management as a continuous process that requires sustained investment in training, mentoring, and refresher education for all team members.
Research
My research focuses on improving the diagnosis and treatment of both drug-susceptible and drug-resistant tuberculosis. I have a particular interest in rapid diagnostics and laboratory strengthening, especially in high-burden settings. More broadly, I conduct implementation research to improve the cascade of care for infectious and non-infectious diseases through enhanced diagnostics, strengthened linkage to care, and community-based interventions—including those integrating social protection.