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Dr Katharina Kranzer

Clinical Associate Professor in Infectious Disease Epidemiology

United Kingdom

 

Based in Harare, Zimbabwe, I serve as Director of the Health Research Unit Zimbabwe (), part of the Biomedical Research and Training Institute (BRTI). I hold academic appointments at the °®ÍþÄÌapp of Hygiene & Tropical Medicine and Ludwig Maximilian University of Munich.

My research focuses on tuberculosis (TB), antimicrobial resistance, and health systems in high-burden settings. My PhD (Wellcome Trust-funded, 2008–2011) examined active TB case finding and ART for TB control in high HIV prevalence contexts. From 2015 to 2018, I directed Germany’s National and WHO Supranational TB Reference Laboratory at the Research Centre Borstel.

I co-lead the EDCTP-funded study with Dr. Norbert Heinrich, aiming to evaluate novel diagnostic tools for early TB detection and targeted preventive treatment. I also serve as Chief Scientist on the TB-CAPT cluster-randomised trial, assessing the impact of near-patient diagnostics (Omni Xpert/Ultra) on treatment initiation timelines.

My work in antimicrobial resistance includes studies in Harare with Dr. Tom Darton (University of Sheffield) and Dr. Justin Dixon, evaluating the impact of the 2019 typhoid conjugate vaccine campaign on antibiotic prescribing.

I contribute to global policy as a member of WHO guideline development groups on TB screening, diagnostics, and testing tools.

I am deeply committed to research capacity development. I co-direct the Africa Health Research Training Programme () African matched fellowship scheme, and lead the Southern African Research Capacity Network (), supporting emerging researchers across the region.

Affiliations

Department of Clinical Research
Faculty of Infectious and Tropical Diseases

°®ÍþÄÌapp

Centre for Evaluation
TB Centre

Teaching

I have a longstanding and active commitment to teaching, training, and research capacity strengthening. I previously served as module organiser and lecturer for the HIV module at LSHTM in London and have contributed as a tutor to the distance learning MSc in Epidemiology for over a decade. I also supervise MSc student projects and (co)supervise several PhD and DrPH students, the majority of whom are based in Zimbabwe and engaged in field-based research.

I am a faculty member on the NIH Fogarty Training for Research Excellence and Mentorship in Tuberculosis (TRENT) programme in Zimbabwe. I serve as co-director of the CREATE PhD programme in Zimbabwe and co-lead, together with Professor Helen Ayles, the CREATE stream supporting matched African fellows. Additionally, I coordinate the EDCTP-funded SOFAR Fellowship Programme, which supports the training of four MSc students, six PhD fellows, and five postdoctoral researchers across Zimbabwe, Zambia, and Mozambique.

My work is underpinned by a strong commitment to capacity building in public health and laboratory systems. During my tenure as Director of the WHO Supranational Tuberculosis Reference Laboratory, I established collaborative partnerships with national and regional laboratories in Moldova, Azerbaijan, Armenia, Sierra Leone, Pakistan, and Ghana. This included delivering in-country training on molecular diagnostics, laboratory information systems, and quality management, alongside supervisory and technical support visits.

In Zimbabwe, I have led the development of a diagnostic blood and urine culture service at the Biomedical Research and Training Institute (BRTI). I am actively involved in laboratory-based training, including bench supervision, regular bench rounds, and structured feedback on standard operating procedures developed by junior staff. I view laboratory quality management as a continuous process that requires sustained investment in training, mentoring, and refresher education for all team members.

Research

My research focuses on improving the diagnosis and treatment of both drug-susceptible and drug-resistant tuberculosis. I have a particular interest in rapid diagnostics and laboratory strengthening, especially in high-burden settings. More broadly, I conduct implementation research to improve the cascade of care for infectious and non-infectious diseases through enhanced diagnostics, strengthened linkage to care, and community-based interventions—including those integrating social protection.

Research Area
Adolescent health
Bacteria
Clinical trials
Diagnostics
Global Health
Sexual and reproductive health
Bacteriology
Epidemiology
Capacity development
Disease and Health Conditions
HIV/AIDS
Tuberculosis
Infectious diseases
Sexually transmitted infections
Country
Mozambique
Tanzania
Zimbabwe
Region
European Union
South Asia
Sub-Saharan Africa (all income levels)

Selected Publications

KRANZER, K; SIMMS, V; Dauya, E; OLARU, ID; DZIVA CHIKWARI, C; MARTIN, K; Redzo, N; Bandason, T; TEMBO, M; Francis, SC; WEISS, HA; HAYES, RJ; Mavodza, C; Apollo, T; Ncube, G; Machiha, A; FERRAND, RA;
2021
BMC Infectious Diseases
Kavenga, F; RICKMAN, HM; Chingono, R; TARUVINGA, T; Marembo, T; Manasa, J; Marambire, E; McHugh, G; Gregson, CL; Bandason, T; Redzo, N; Maunganidze, A; Magure, T; Ndhlovu, C; Mujuru, H; Rusakaniko, S; Manangazira, P; FERRAND, RA; KRANZER, K;
2021
PloS one
Fryatt, A; SIMMS, V; Bandason, T; Redzo, N; OLARU, ID; Ndhlovu, CE; Mujuru, H; Rusakaniko, S; Hoelscher, M; Rubio-Acero, R; Paunovic, I; Wieser, A; Chonzi, P; Masunda, K; FERRAND, RA; KRANZER, K;
2021
EClinicalMedicine
RICHARDS, AS; Sossen, B; EMERY, JC; HORTON, KC; Heinsohn, T; Frascella, B; Balzarini, F; Oradini-Alacreu, A; Hacker, B; Odone, A; MCCREESH, N; GRANT, AD; KRANZER, K; Cobelens, F; Esmail, H; HOUBEN, RM G J;
2021
KHAN, P; BAISLEY, K; Martinez, L; Mzembe, T; Chiumya, R; KRANZER, K; Fine, P; Fielding, K; Crampin, A; Glynn, J;
2021
SSM Annual Scientific Meeting
OLARU, ID; Chisenga, M; YEUNG, S; MABEY, D; MARKS, M; Chonzi, P; Masunda, KP; Machiha, A; FERRAND, RA; KRANZER, K;
2021
BMJ open
OLARU, ID; FERRAND, RA; Chisenga, M; YEUNG, S; Macrae, B; Chonzi, P; STABLER, RA; HOPKINS, H; MABEY, D; Masunda, KP E; KRANZER, K;
2021
JAC-antimicrobial resistance
Chimhini, G; OLARU, ID; Fitzgerald, F; Chisenga, M; Ferreyra, C; Malou, N; Piton, J; Chimhuya, S; YEUNG, S; De, S; Mujuru, HA; KRANZER, K;
2021
The Pediatric infectious disease journal
OLARU, ID; Tacconelli, E; YEUNG, S; FERRAND, RA; STABLER, RA; HOPKINS, H; AIKEN, AM; KRANZER, K;
2021
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases
KHAN, MS; REGO, S; Rajal, JB; BOND, V; Fatima, RK; Isani, AK; SUTHERLAND, J; KRANZER, K;
2021
PLoS One