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Dr Alex Keeley

Clinical Research Fellow in Training

United Kingdom

I am a Wellcome Trust PhD Fellow in Global Health and an Infectious Diseases and General Medicine doctor in training. My research focuses on the epidemiology and immunology of Streptococcus pyogenes (Strep A) in high-burden, resource-limited settings, with the ultimate goal of informing vaccine strategies to combat Strep A associated diseases including rheumatic heart disease (RHD) and severe invasive infections.

Affiliations

Department of Clinical Research
Faculty of Infectious and Tropical Diseases

Research

My research focuses on the epidemiology and immunology of Strep A. I aim to understand the role of natural immunity to Strep A to guide the development of effective vaccine strategies. My research investigates naturally occurring immune responses to candidate vaccine antigens in populations with high disease burdens, particularly in The Gambia.

Selected Publications

De Crombrugghe, G; Armitage, EP; KEELEY, AJ; Senghore, E; Camara, F; Jammeh, M; Bittaye, A; Ceesay, H; Ceesay, I; Samateh, B; Manneh, M; Botquin, G; Lakhloufi, D; Delforge, V; Bah, SY; Hall, JN; Schiavolin, L; Turner, CE; MARKS, M; De Silva, TI; Botteaux, A; Smeesters, PR; Sesay, AK; Bah, S; Kampmann, B; ... Antonio, M.
2025
The Journal of infectious diseases
Locke, TE; KEELEY, AJ; Laundy, N; Keil, C; Hamilton, J; Pandor, A; I de Silva, T; Darton, TC;
2025
The Journal of infection
KEELEY, A; Camara, F; Armitage, E; De Crombrugghe, G; Sillah, J; Fofana, ML; Rollinson, V; Senghore, E; Jammeh, M; Whitcombe, A; Bittaye, A; Ceesay, H; Ceesay, I; Samateh, B; Manneh, M; Carducci, M; Rovetini, L; Boero, E; Massai, L; Sanyang, C; Camara, O; Cessay, E; Iturriza, M; Gomes, DM; Kucharski, A; ... De Silva, T.
2025
medRxiv
Massai, L; Carducci, M; Rovetini, L; Paterson, A; Whitcombe, A; McGregor, R; Lorenz, N; KEELEY, AJ; DE SILVA, TI; Bennett, J; Berlanda Scorza, F; Iturriza, M; Moreland, NJ; Moriel, DG; Rossi, O;
2024
Journal of immunological methods
Hall, JN; ARMITAGE, EP; Senghore, E; DARBOE, S; Barry, M; Camara, J; Bah, S; KEELEY, AJ; McCarthy, JS; Smeesters, P; Turner, CE; Darton, TC; MARKS, M; Angyal, A; DE SILVA, TI;
2024
The Journal of infectious diseases
ARMITAGE, EP; De Crombrugghe, G; KEELEY, AJ; Senghore, E; Camara, FE; Jammeh, M; Bittaye, A; Ceesay, H; Ceesay, I; Samateh, B; Manneh, M; KAMPMANN, B; Turner, CE; KUCHARSKI, A; Botteaux, A; Smeesters, PR; DE SILVA, TI; MARKS, M; MRCG StrepA Study Group,;
2024
The Lancet. Microbe
Suau Sans, M; Manneh, M; Ceesay, I; Bittaye, A; De Crombrugghe, G; KEELEY, AJ; De Silva, TI; PALMER, J; ARMITAGE, E; MARKS, M;
2024
PLOS Global Public Health
Suau Sans, M; Manneh, M; Ceesay, I; Bittaye, A; De Crombrugghe, G; KEELEY, AJ; DE SILVA, TI; PALMER, J; ARMITAGE, EP; MARKS, M; MRCG Strep A Study Group,;
2024
PLOS Glob Public Health
Boero, E; Carducci, M; KEELEY, AJ; Berlanda Scorza, F; Iturriza-Gómara, M; Moriel, DG; Rossi, O;
2024
Journal of immunological methods
Hall, JN; Armitage, E; Senghore, E; DARBOE, S; Barry, M; Camara, J; Bah, S; KEELEY, A; McCarthy, J; Smeesters, P; Turner, C; Darton, T; Marks, M; Angyal, A; De Silva, T;
2024
medRxiv