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Roly is a Professor in Global Health with an interest in malaria control and elimination and health systems strengthening through the use of quality and process improvement. He has more than 25 years experience in malaria clinical trials, chemoprevention, programmatic policy and strategy, health financing and much more. He was the director of the Malaria Elimination Initiative at the University of California San Francisco between 2011- 2021 where he led a team of researchers in all aspects of malaria elimination developing the Malaria Elimination Toolkit (), supported the development of regional initiatives for malaria elimination (Asia Pacific Malaria Elimination Network and the Southern African Development Communities Elimination 8 (E8)), was invovled in several influential publications supporting the move towards malaria elimination and eradication goals. At LSHTM he has lead the Unitaid Plus project in collaboration with Population Services International, evaluating large scale pilot roll out of perennial malaria chemoprevention (PMC) and now leads the new OPTiMIX project - Optimising the mix of malaria interventions including malaria vaccines, malaria chemoprevention and PBO-LLINS.