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Professor David Baker

Professor of Malaria Parasite Biology

United Kingdom

Jump to: Affiliations Teaching Research Publications

David Baker has a BSc in Zoology and has a PhD that focused on the Molecular Biology of the intestinal parasite Giardia lamblia from the University of Hull in 1988. He then moved to the °®ÍþÄÌapp of Hygiene & Tropical Medicine to work on the malaria parasite Plasmodium falciparum. David became a Professor of Malaria Parasite Biology at the School in 2015. He holds current Wellcome Trust Investigator and Innovator Awards.

Affiliations
Department of Infection Biology
Faculty of Infectious and Tropical Diseases

°®ÍþÄÌapp

Malaria Centre
Antimicrobial Resistance Centre

Teaching

Each year David lectures on the Advanced Practical Training in Molecular Biology Masters module (3158). He is a Tutor for the Distance Learning MSc, Postgraduate Diploma & Certificate in Infectious Diseases, and Tutor for the MSc in Medical Microbiology. David also marks exam scripts, assignments and MSc summer projects each year.

Research
David Baker's research team use molecular and biochemical approaches to deliver an understanding of the role of cyclic nucleotide signalling in controlling the malaria parasite life cycle. He also partners chemists at Salvensis and the Medicines for Malaria Venture (MMV) to develop small molecule inhibitors that target cyclic nucleotide signalling with the longer term aim of developing a new antimalarial drug.
Research Area
Drug discovery and development
Drug resistance
Parasites
Protozoa
Biochemistry
Cell biology
Genetics
Microbiology
Molecular biology
Parasitology
Disease and Health Conditions
Malaria

Selected Publications
Balestra, AC; Koussis, K; Klages, N; Howell, SA; Flynn, HR; Bantscheff, M; Pasquarello, C; Perrin, AJ; Brusini, L; Arboit, P; Sanz, O; Castaño, LP-B; Withers-Martinez, C; Hainard, A; Ghidelli-Disse, S; Snijders, AP; BAKER, DA; BLACKMAN, MJ; Brochet, M;
2021
Science advances
Nofal, SD; PATEL, A; BLACKMAN, MJ; Flueck, C; BAKER, DA;
2021
mBio
Camarda, G; Jirawatcharadech, P; Priestley, RS; Saif, A; March, S; Wong, MH L; Leung, S; Miller, AB; BAKER, DA; Alano, P; Paine, MJ I; Bhatia, SN; O'Neill, PM; Ward, SA; Biagini, GA;
2019
Nature Communications
El Bakkouri, M; Kouidmi, I; Wernimont, AK; Amani, M; Hutchinson, A; Loppnau, P; Kim, JJ; FLUECK, C; Walker, JR; Seitova, A; Senisterra, G; Kakihara, Y; Kim, C; BLACKMAN, MJ; Calmettes, C; BAKER, DA; Hui, R;
2019
Proceedings of the National Academy of Sciences of the United States of America
MOHRING, F; Hart, MN; Rawlinson, TA; Henrici, R; CHARLESTON, JA; DIEZ BENAVENTE, E; PATEL, A; Hall, J; Almond, N; CAMPINO, S; CLARK, TG; SUTHERLAND, CJ; BAKER, DA; Draper, SJ; MOON, RW;
2019
eLife
PATEL, A; Perrin, AJ; Flynn, HR; Bisson, C; Withers-Martinez, C; Treeck, M; FLUECK, C; Nicastro, G; Martin, SR; Ramos, A; Gilberger, TW; Snijders, AP; BLACKMAN, MJ; BAKER, DA;
2019
PLoS biology
FLUECK, C; Drought, LG; Jones, A; PATEL, A; Perrin, AJ; Walker, EM; NOFAL, SD; Snijders, AP; BLACKMAN, MJ; BAKER, DA;
2019
PLoS Biology
Fang, H; Gomes, AR; Klages, N; Pino, P; Maco, B; WALKER, EM; Zenonos, ZA; Angrisano, F; Baum, J; Doerig, C; BAKER, DA; Billker, O; Brochet, M;
2018
Nature communications
Perrin, AJ; Collins, CR; Russell, MR G; Collinson, LM; BAKER, DA; BLACKMAN, MJ;
2018
mBio
BAKER, DA; STEWART, LB; Large, JM; Bowyer, PW; Ansell, KH; Jiménez-Díaz, MB; El Bakkouri, M; Birchall, K; Dechering, KJ; Bouloc, NS; Coombs, PJ; Whalley, D; Harding, DJ; Smiljanic-Hurley, E; Wheldon, MC; WALKER, EM; DESSENS, JT; Lafuente, MJ; Sanz, LM; Gamo, F-J; Ferrer, SB; Hui, R; Bousema, T; Angulo-Barturén, I; Merritt, AT; ... Osborne, SA.
2017
Nature communications
David Baker

Contact

United Kingdom